Higher urine-to-plasma urea ratio reflects heightened risk of chronic kidney disease (CKD) progression

Higher urine-to-plasma urea ratio reflects heightened risk of chronic kidney disease (CKD) progression

In a large cohort of patients with common forms of chronic kidney disease (CKD), researchers found that urine-to-plasma ratio of urea ([U/P]urea) was independently associated with CKD progression and kidney failure.

An association of urinary concentrating capacity with CKD progression, independently of glomerular filtration rate (GFR), supports the notion that a more comprehensive assessment of kidney function than is typically performed in clinical practice today, might improve risk prediction…. [read more]

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